All Industry/Business Updates
Write a BlogDevelopment of Nanobody-Based Drug Delivery Systems
Date: 28/08/2024
Post By: Linna Green
Nanobodies are small antibody fragments derived from naturally occurring heavy-chain antibodies found in camelids, such as camels and llamas. They are composed of a single monomeric variable domain, making them much smaller than conventional antibodies. The development of nanobody-based drug delivery systems began with the discovery of camelid antibodies in the early 1990s. These ant...
Read MoreCommon Methods for Drug Conjugation
Date: 28/08/2024
Post By: Linna Green
Drug conjugation is a crucial method used in pharmaceutical research and development to enhance the pharmacokinetic and pharmacodynamic properties of a drug. By attaching various molecules to the drug (antibody conjugation, PEGylation, oligonucleotide bioconjugation, etc.), researchers can improve its solubility, stability, targeting ability, and overall therapeutic efficacy. There are s...
Read MoreApplications of Stable Isotope Labeled Amino Acids in Biological and Medical Research
Date: 28/08/2024
Post By: Linna Green
Stable isotope labeled amino acids have emerged as indispensable tools for researchers in the fields of biology and medicine, offering unique opportunities to delve into complex biological processes at the molecular level. These specially labeled amino acids, though chemically identical to their natural counterparts, possess isotopic substitutions that make them easily distinguishable and tra...
Read MoreCreative BioMart Expands Native Proteins Offering to Advance Scientific Research and Discovery
Date: 27/07/2024
Post By: Creative BioMart
Creative BioMart, a leading provider of recombinant and native proteins, today announced a significant expansion of its native proteins product line. The company has added numerous proteins from various species and sources to its portfolio, underscoring its commitment to supporting researchers in academia, biotech, and pharma. Native proteins, also known as natural proteins, are purified ...
Read MoreThe Mysterious Case of the SPR Protein: Unraveling its Role in Human Health
Date: 27/07/2024
Post By: Creative BioMart
The human body is a complex machine, composed of billions of cells, each performing unique functions to keep us alive. At the heart of these cellular processes are proteins – the building blocks of life. One such protein, known as the Short-Patch Repair (SPR) protein, has recently garnered significant attention due to its potential link to various diseases. But what exactly is the SPR protei...
Read MoreDesign and Synthesis of Hydrophobic Amino Acids
Date: 17/07/2024
Post By: Linna Green
Hydrophobic amino acids are vital components in the realm of protein structure and function. While hydrophilic amino acids establish interactions with water molecules in the cellular environment, hydrophobic amino acids tend to congregate in the interior of proteins, contributing to their three-dimensional fold and stability. The synthesis of hydrophobic amino acids involves in...
Read MoreA Look at Some Common Natural Constituents and Their Pharmacological Benefits
Date: 17/07/2024
Post By: Linna Green
Among these, sulforaphane, flavonoids, and bakuchiol have emerged as promising natural constituents with a wide range of pharmacological benefits. These compounds have been studied extensively for their antioxidant, anti-inflammatory, and anti-cancer properties, highlighting their potential as natural alternatives for various health conditions. Sulforaphane is a sulfur-containing com...
Read MoreExploring the Methods of RNA Synthesis in Molecular Biology
Date: 17/07/2024
Post By: Linna Green
These custom RNA molecules play crucial roles in a wide range of applications, including gene expression studies, functional genomics, and RNA interference experiments. The process of custom RNA synthesis involves the production of RNA molecules with precise sequences and modifications, enabling researchers to investigate various biological processes with high specificity and efficiency. &nb...
Read MoreAn Overview of Functional Peptides
Date: 28/06/2024
Post By: Caroline Miller
If we were to delve into the intricate world of biochemistry, we would come across the functionality of diverse molecules that perform essential roles in biological systems. One such class of molecules, peptides, are short chains of amino acid monomers linked by peptide bonds. These aren't just any ordinary molecules; these are functional peptides which undeniably contribute a significant part to ...
Read MoreCommon Natural Constituents and Their Pharmacological Benefits
Date: 28/06/2024
Post By: Linna Green
Among these, sulforaphane, flavonoids, and bakuchiol have emerged as promising natural constituents with a wide range of pharmacological benefits. These compounds have been studied extensively for their antioxidant, anti-inflammatory, and anti-cancer properties, highlighting their potential as natural alternatives for various health conditions. Sulforaphane is a sulfur-containing com...
Read MoreIsotopic Labeling in Molecular Research
Date: 28/06/2024
Post By: Linna Green
Isotopic labeling is a powerful technique employed in molecular biology, biochemistry, and related fields to trace the movement of atoms within molecules, elucidate metabolic pathways, and study biological processes. By replacing the naturally occurring isotopes of elements with their stable isotopic counterparts, researchers can track the fate of specific atoms in a compound, enabling detail...
Read MoreInnovative Approaches to AAV Formulation Development
Date: 28/06/2024
Post By: Linna Green
AAV Formulation Development: A Primary Focus In the field of gene therapy, AAV formulation development has gained significant focus. AAV vectors are used as delivery vehicles or "vectors" to administer therapeutic genes into patient's cells. This therapeutic gene, once inside the cell, generates a functional protein to correct or counter the effects of the disease-causing genetic mutation...
Read MoreRibonuclease 1: A Key Player in RNA Degradation
Date: 26/06/2024
Post By: Creative BioMart
The RNASE1 gene encodes a member of the ribonuclease A superfamily. The encoded protein is a monomeric ribonuclease with specificity for uridine residues at the 3'-side of the scission site. This enzyme cleaves RNA, initiating a degradation pathway that ultimately leads to the destruction of the RNA molecule. Ribonucleases play essential roles in various aspects of RNA metabolism, including RNA pr...
Read MoreMicrotubule-Associated Protein Tau: Structure, Function, and Role in Neurodegenerative Diseases
Date: 26/06/2024
Post By: Creative BioMart
Microtubule-associated protein tau (MAPT) is a crucial protein in the human brain, playing a central role in the development and maintenance of neuronal microtubules. It is encoded by the MAPT gene and is primarily expressed in neurons. Tau protein's main function is to stabilize and promote the assembly of microtubules, which are part of the cytoskeleton and provide structure and shape to cells. ...
Read MoreUnraveling the Mysteries of TREM1 Protein: A Key Player in Inflammation and Disease
Date: 28/05/2024
Post By: Creative BioMart
The Triggering receptor expressed on myeloid cells 1 (TREM1) protein has emerged as a pivotal player in the intricate web of immunological responses, particularly in the context of inflammatory diseases. Unraveling the mysteries of TREM1 entails delving into its structure, function, and implications in various pathological conditions, shedding light on its potential as a therapeutic target.  ...
Read MoreExploring the Thyroid-Stimulating Hormone (TSH): Master Regulator of Thyroid Function
Date: 28/05/2024
Post By: Creative BioMart
Introduction of TSH The Thyroid-Stimulating Hormone (TSH) protein is a crucial player in the regulation of thyroid function. In this blog post, we will explore the structure, function, and significance of TSH in maintaining a healthy thyroid. Structure of TSH Let's start by understanding the structure and function of TSH. TSH, also known as thyrotropin, is a glycoprotein hormone secrete...
Read MoreThe Sweet Side of Proteins: N-Linked Oligosaccharide Synthesis
Date: 28/05/2024
Post By: CD BioGlyco
When you think of proteins, you might picture long chains of amino acids, the building blocks of life. But many proteins have an extra layer of complexity – carbohydrate molecules attached to them. These protein-bound sugars play crucial roles in folding, stability, and function. One type of carbohydrate attachment, known as N-linked glycosylation, involves the addition of oligosaccharides (...
Read MoreCD BioGlyco Updated Its Custom Polysaccharide Synthesis Service Recently
Date: 28/05/2024
Post By: CD BioGlyco
CD BioGlyco, a leading provider of glycobiology-related products and services, has announced updates to its custom polysaccharide synthesis service. This enhanced service will provide researchers with even greater flexibility and capabilities in synthesizing complex polysaccharides tailored to their specific research needs. Polysaccharides, the most abundant biopolymers on earth, play cru...
Read Moresodium bicarbonate factory
Date: 28/04/2024
Post By: Cristina
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Read MoreGlycoprotein Quantification: Shedding Light on Protein Glycosylation
Date: 27/04/2024
Post By: CD BioGlyco
Proteins are the workhorses of the cell, carrying out a wide range of functions essential for life. However, proteins rarely exist in their naked form. Instead, they are often adorned with complex sugar molecules, a process known as glycosylation. Glycoproteins, as they are called, play critical roles in various biological processes, including cell signaling, immune response, and protein folding. ...
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